CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Parathion hydrolase

Enzyme Information

3.1.8.1
Aryldialkylphosphatase.
based on mapping to UniProt P0A434
An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.
-!- Acts on organophosphorus compounds (such as paraoxon) including esters of phosphonic and phosphinic acids. -!- Inhibited by chelating agents. -!- Previously regarded as identical with EC 3.1.1.2.

UniProtKB Entries (1)

P0A434
OPD_BREDI
Brevundimonas diminuta
Parathion hydrolase

PDB Structure

PDB 3E3H
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities.
Reeves, T.E., Wales, M.E., Grimsley, J.K., Li, P., Cerasoli, D.M., Wild, J.R.
Protein Eng.Des.Sel.