CATH Classification

Domain Context

CATH Clusters

Superfamily Divalent-metal-dependent TIM barrel enzymes
Functional Family

Enzyme Information

4.2.1.118
3-dehydroshikimate dehydratase.
based on mapping to UniProt Q81RQ4
3-dehydro-shikimate = protocatechuate + H(2)O.
-!- Catalyzes an early step in the biosynthesis of petrobactin, a siderophore produced by many bacteria, including the human pathogen Bacillus anthracis.

UniProtKB Entries (1)

Q81RQ4
ASBF_BACAN
Bacillus anthracis
3-dehydroshikimate dehydratase

PDB Structure

PDB 3DX5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Pfleger, B.F., Kim, Y., Nusca, T.D., Maltseva, N., Lee, J.Y., Rath, C.M., Scaglione, J.B., Janes, B.K., Anderson, E.C., Bergman, N.H., Hanna, P.C., Joachimiak, A., Sherman, D.H.
Proc.Natl.Acad.Sci.USA