CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family pleckstrin homology domain-containing family M member 2

Enzyme Information

UniProtKB Entries (2)

Q8IWE5
PKHM2_HUMAN
Homo sapiens
Pleckstrin homology domain-containing family M member 2
Q56061
SIFA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Secreted effector protein SifA

PDB Structure

PDB 3CXB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation
Ohlson, M.B., Huang, Z., Alto, N.M., Blanc, M.P., Dixon, J.E., Chai, J., Miller, S.I.
Cell Host Microbe