CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family Glutamate receptor ionotropic, kainate 2

Enzyme Information

UniProtKB Entries (1)

P19491
GRIA2_RAT
Rattus norvegicus
Glutamate receptor 2

PDB Structure

PDB 3BKI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor.
Cruz, L.A., Estebanez-Perpina, E., Pfaff, S., Borngraeber, S., Bao, N., Blethrow, J., Fletterick, R.J., England, P.M.
J.Med.Chem.