CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family

Enzyme Information

UniProtKB Entries (1)

P19491
GRIA2_RAT
Rattus norvegicus
Glutamate receptor 2

PDB Structure

PDB 3BFU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency.
Beich-Frandsen, M., Pickering, D.S., Mirza, O., Johansen, T.N., Greenwood, J., Vestergaard, B., Schousboe, A., Gajhede, M., Liljefors, T., Kastrup, J.S.
J.Med.Chem.