CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate-binding domains
Functional Family Oxaloacetate decarboxylase

Enzyme Information

4.1.1.112
Oxaloacetate decarboxylase.
based on mapping to UniProt Q9HUU1
Oxaloacetate = pyruvate + CO(2).
-!- The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+). -!- Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport. -!- Formerly EC 4.1.1.3.

UniProtKB Entries (1)

Q9HUU1
OADC_PSEAE
Pseudomonas aeruginosa PAO1
Oxaloacetate decarboxylase

PDB Structure

PDB 3B8I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily.
Narayanan, B.C., Niu, W., Han, Y., Zou, J., Mariano, P.S., Dunaway-Mariano, D., Herzberg, O.
Biochemistry