CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Engulfment and cell motility protein 1

Enzyme Information

UniProtKB Entries (1)

Q92608
DOCK2_HUMAN
Homo sapiens
Dedicator of cytokinesis protein 2

PDB Structure

PDB 3A98
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Hanawa-Suetsugu, K., Kukimoto-Niino, M., Mishima-Tsumagari, C., Akasaka, R., Ohsawa, N., Sekine, S., Ito, T., Tochio, N., Koshiba, S., Kigawa, T., Terada, T., Shirouzu, M., Nishikimi, A., Uruno, T., Katakai, T., Kinashi, T., Kohda, D., Fukui, Y., Yokoyama, S.
Proc.Natl.Acad.Sci.USA