CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family tRNA dimethylallyltransferase

Enzyme Information

2.5.1.75
tRNA dimethylallyltransferase.
based on mapping to UniProt P16384
Dimethylallyl diphosphate + adenine(37) in tRNA = diphosphate + N(6)- dimethylallyladenine(37) in tRNA.
-!- Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate. -!- Formerly EC 1.8.6.1 and EC 2.5.1.8.

UniProtKB Entries (1)

P16384
MIAA_ECOLI
Escherichia coli K-12
TRNA dimethylallyltransferase

PDB Structure

PDB 2ZM5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon
Chimnaronk, S., Forouhar, F., Sakai, J., Yao, M., Tron, C.M., Atta, M., Fontecave, M., Hunt, J.F., Tanaka, I.
Biochemistry