CATH Domain 2ys5A01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family

Enzyme Information

UniProtKB Entries (1)

ALK_HUMAN

Homo sapiens

ALK tyrosine kinase receptor

PDB Structure

PDB	2YS5
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 Koshiba, S., Li, H., Motoda, Y., Tomizawa, T., Kasai, T., Tochio, N., Yabuki, T., Harada, T., Watanabe, S., Tanaka, A., Shirouzu, M., Kigawa, T., Yamamoto, T., Yokoyama, S. J.Struct.Funct.Genom.