CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

2.3.1.247
3-keto-5-aminohexanoate cleavage enzyme.
based on mapping to UniProt B0VHH0
(5S)-5-amino-3-oxohexanoate + acetyl-CoA = L-3-aminobutanoyl-CoA + acetoacetate.
-!- The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine.

UniProtKB Entries (1)

B0VHH0
KCE_CLOAI
Candidatus Cloacimonas acidaminovorans str. Evry
3-keto-5-aminohexanoate cleavage enzyme

PDB Structure

PDB 2Y7G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation.
Bellinzoni, M., Bastard, K., Perret, A., Zaparucha, A., Perchat, N., Vergne, C., Wagner, T., De Melo-Minardi, R.C., Artiguenave, F., Cohen, G.N., Weissenbach, J., Salanoubat, M., Alzari, P.M.
J.Biol.Chem.