CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family

Enzyme Information

UniProtKB Entries (1)

P19491
GRIA2_RAT
Rattus norvegicus
Glutamate receptor 2

PDB Structure

PDB 2XXH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators.
Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., Harris, A.J., Harrison, S.A., Melarange, R.A., Mookherjee, C., Mosley, J., Dal Negro, G., Oliosi, B., Smith, K.J., Thewlis, K.M., Woollard, P.M., Yusaf, S.P.
J.Med.Chem.