CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Eukaryotic initiation factor 4A-III

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P38919
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q9BZI7
REN3B_HUMAN
Homo sapiens
Regulator of nonsense transcripts 3B

PDB Structure

PDB 2XB2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Buchwald, G., Ebert, J., Basquin, C., Sauliere, J., Jayachandran, U., Bono, F., Le Hir, H., Conti, E.
Proc.Natl.Acad.Sci.USA