CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family dynamin-1 isoform X2

Enzyme Information

3.6.5.5
Dynamin GTPase.
based on mapping to UniProt Q05193
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

Q05193
DYN1_HUMAN
Homo sapiens
Dynamin-1

PDB Structure

PDB 2X2F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity.
Chappie, J.S., Acharya, S., Leonard, M., Schmid, S.L., Dyda, F.
Nature