CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family serine/threonine-protein kinase OSR1 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O95747
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q96J92
WNK4_HUMAN
Homo sapiens
Serine/threonine-protein kinase WNK4

PDB Structure

PDB 2V3S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights Into the Recognition of Substrates and Activators by the Osr1 Kinase
Villa, F., Goebel, J., Rafiqi, F.H., Deak, M., Thastrup, J., Alessi, D.R., Van Aalten, D.M.F.
Embo Rep.