CATH Classification

Domain Context

CATH Clusters

Superfamily Hotdog Thioesterase
Functional Family Cytosolic acyl coenzyme A thioester hydrolase

Enzyme Information

3.1.2.2
Palmitoyl-CoA hydrolase.
based on mapping to UniProt Q91V12
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.

UniProtKB Entries (1)

Q91V12
BACH_MOUSE
Mus musculus
Cytosolic acyl coenzyme A thioester hydrolase

PDB Structure

PDB 2V1O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Recruitment of Tandem Hotdog Domains in Acyl-Coa Thioesterase 7 and its Role in Inflammation.
Forwood, J.K., Thakur, A.S., Guncar, G., Marfori, M., Mouradov, D., Meng, W.N., Robinson, J., Huber, T., Kellie, S., Martin, J.L., Hume, D.A., Kobe, B.
Proc.Natl.Acad.Sci.USA