CATH Domain 2uvqA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Uridine-cytidine kinase 2

Enzyme Information

2.7.1.48

Uridine kinase.

based on mapping to UniProt Q9HA47

ATP + uridine = ADP + UMP.

-!- Cytidine can act as acceptor. -!- GTP and ITP can act as donors.

UniProtKB Entries (1)

UCK1_HUMAN

Homo sapiens

Uridine-cytidine kinase 1

PDB Structure

PDB	2UVQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of Human Uridine-Cytidine Kinase 1 Kosinska, U., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E.P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P. To be Published