CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

P01112
RASH_HUMAN
Homo sapiens
GTPase HRas

PDB Structure

PDB 2QUZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation.
Denayer, E., Parret, A., Chmara, M., Schubbert, S., Vogels, A., Devriendt, K., Frijns, J.P., Rybin, V., de Ravel, T.J., Shannon, K., Cools, J., Scheffzek, K., Legius, E.
Hum.Mutat.