1 keywords

CATH Domain 2qq2C00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.10 Roll
Topology 3.10.129 Thiol Ester Dehydrase; Chain A
Homologous Superfamily 3.10.129.10 Hotdog Thioesterase

Domain Context

CATH Clusters

Superfamily Hotdog Thioesterase
Functional Family Cytosolic acyl coenzyme A thioester hydrolase

Enzyme Information

3.1.2.2
Palmitoyl-CoA hydrolase.
based on mapping to UniProt O00154
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.

UniProtKB Entries (1)

O00154
BACH_HUMAN
Homo sapiens
Cytosolic acyl coenzyme A thioester hydrolase

PDB Structure

PDB 2QQ2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Human acyl-CoA thioesterase 7.
Busam, R., Lehtio, L., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A., Flodin, S., Flores, A., Greslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Persson, C.
To be Published