CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family spermatogenesis-associated protein 13 isoform X2

Enzyme Information

UniProtKB Entries (1)

Q9NR80
ARHG4_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 4

PDB Structure

PDB 2PZ1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Mitin, N., Betts, L., Yohe, M.E., Der, C.J., Sondek, J., Rossman, K.L.
Nat.Struct.Mol.Biol.