CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Rho guanine nucleotide exchange factor (GEF) 7

Enzyme Information

UniProtKB Entries (2)

O55043
ARHG7_RAT
Rattus norvegicus
Rho guanine nucleotide exchange factor 7
Q96J02
ITCH_HUMAN
Homo sapiens
E3 ubiquitin-protein ligase Itchy homolog

PDB Structure

PDB 2P4R
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domain.
Janz, J.M., Sakmar, T.P., Min, K.C.
J.Biol.Chem.