CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Putative src kinase-associated phosphoprotein 2

Enzyme Information

UniProtKB Entries (1)

Q3UND0
SKAP2_MOUSE
Mus musculus
Src kinase-associated phosphoprotein 2

PDB Structure

PDB 2OTX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch.
Swanson, K.D., Tang, Y., Ceccarelli, D.F., Poy, F., Sliwa, J.P., Neel, B.G., Eck, M.J.
Mol.Cell