CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family Serine/threonine-protein kinase WNK1 isoform 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9JIH7
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9JIH7
WNK1_RAT
Rattus norvegicus
Serine/threonine-protein kinase WNK1

PDB Structure

PDB 2LRU
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution Structure of the WNK1 Autoinhibitory Domain, a WNK-Specific PF2 Domain.
Moon, T.M., Correa, F., Kinch, L.N., Piala, A.T., Gardner, K.H., Goldsmith, E.J.
J.Mol.Biol.