CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DBP5

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P20449
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P20449
DBP5_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase DBP5

PDB Structure

PDB 2KBE
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
Fan, J.S., Cheng, Z., Zhang, J., Noble, C., Zhou, Z., Song, H., Yang, D.
J.Mol.Biol.