CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Eukaryotic initiation factor 4A-III

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P38919
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P38919
IF4A3_HUMAN
Homo sapiens
Eukaryotic initiation factor 4A-III

PDB Structure

PDB 2HXY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Andersen, C.B., Ballut, L., Johansen, J.S., Chamieh, H., Nielsen, K.H., Oliveira, C.L., Pedersen, J.S., Seraphin, B., Le Hir, H., Andersen, G.R.
Science