CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family |
Enzyme Information
| 2.7.4.25 |
(d)CMP kinase.
based on mapping to UniProt P63807
ATP + (d)CMP = ADP + (d)CDP.
-!- The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor. -!- Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22. -!- The enzyme phosphorylates dCMP nearly as well as it does CMP.
|
UniProtKB Entries (1)
| P63807 |
KCY_STAAW
Staphylococcus aureus subsp. aureus MW2
Cytidylate kinase
|
PDB Structure
| PDB | 2H92 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate.
Acta Crystallogr.,Sect.F
|