CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Estrogen sulfotransferase

Enzyme Information

2.8.2.2
Alcohol sulfotransferase.
based on mapping to UniProt Q6IMI6
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
-!- Primary and secondary alcohols, including aliphatic alcohols, ascorbate, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15).

UniProtKB Entries (1)

Q6IMI6
ST1C3_HUMAN
Homo sapiens
Sulfotransferase 1C3

PDB Structure

PDB 2H8K
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and chemical profiling of the human cytosolic sulfotransferases.
Allali-Hassani, A., Pan, P.W., Dombrovski, L., Najmanovich, R., Tempel, W., Dong, A., Loppnau, P., Martin, F., Thornton, J., Thonton, J., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Vedadi, M., Arrowsmith, C.H.
Plos Biol.