CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

2.4.2.12
Nicotinamide phosphoribosyltransferase.
based on mapping to UniProt Q99KQ4
Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho- alpha-D-ribose 1-diphosphate.

UniProtKB Entries (1)

Q99KQ4
NAMPT_MOUSE
Mus musculus
Nicotinamide phosphoribosyltransferase

PDB Structure

PDB 2H3D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Wang, T., Zhang, X., Bheda, P., Revollo, J.R., Imai, S.I., Wolberger, C.
Nat.Struct.Mol.Biol.