CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | Transcription initiation factor TFIIH subunit |
Enzyme Information
UniProtKB Entries (2)
| P04637 |
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53
|
| P32776 |
TFB1_YEAST
Saccharomyces cerevisiae S288C
General transcription and DNA repair factor IIH subunit TFB1
|
PDB Structure
| PDB | 2GS0 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53.
Mol.Cell
|