CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

Enzyme Information

4.2.1.10
3-dehydroquinate dehydratase.
based on mapping to UniProt Q9SQT8
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q9SQT8
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q9SQT8
DHQSD_ARATH
Arabidopsis thaliana
Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

PDB Structure

PDB 2GPT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase and implications for metabolic channeling in the shikimate pathway
Singh, S.A., Christendat, D.
Biochemistry