CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Hydroxymethylglutaryl-CoA lyase |
Enzyme Information
| 4.1.3.26 |
3-hydroxy-3-isohexenylglutaryl-CoA lyase.
based on mapping to UniProt Q9I2A0
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 7-methyl-3-oxooct-6- enoyl-CoA + acetate.
-!- Also acts on the hydroxy derivative of farnesoyl-CoA.
|
| 4.1.3.4 |
Hydroxymethylglutaryl-CoA lyase.
based on mapping to UniProt Q9I2A0
(S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate.
|
UniProtKB Entries (1)
| Q9I2A0 |
LIUE_PSEAE
Pseudomonas aeruginosa PAO1
3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase
|
PDB Structure
| PDB | 2FTP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa
To be Published
|