CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, B domain
Functional Family Succinate--CoA ligase [ADP-forming] subunit beta

Enzyme Information

6.2.1.4
Succinate--CoA ligase (GDP-forming).
based on mapping to UniProt P53590
GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
-!- Itaconate can act instead of succinate and ITP instead of GTP.

UniProtKB Entries (1)

O19069
SUCA_PIG
Sus scrofa
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

PDB Structure

PDB 2FP4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Interactions of GTP with the ATP-grasp Domain of GTP-specific Succinyl-CoA Synthetase
Fraser, M.E., Hayakawa, K., Hume, M.S., Ryan, D.G., Brownie, E.R.
J.Biol.Chem.