CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2300
Functional Family Low molecular weight protein-tyrosine-phosphatase

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P0AAB2
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P0AAB2
WZB_ECOLI
Escherichia coli K-12
Low molecular weight protein-tyrosine-phosphatase Wzb

PDB Structure

PDB 2FEK
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
The solution structure of Escherichia coli Wzb reveals a novel substrate recognition mechanism of prokaryotic low molecular weight protein-tyrosine phosphatases
Lescop, E., Hu, Y., Xu, H., Hu, W., Chen, J., Xia, B., Jin, C.
J.Biol.Chem.