CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family H-2 class I histocompatibility antigen, alpha chain

Enzyme Information

UniProtKB Entries (1)

P01848
TRAC_HUMAN
Homo sapiens
T cell receptor alpha constant

PDB Structure

PDB 2F54
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Dunn, S.M., Rizkallah, P.J., Baston, E., Mahon, T., Cameron, B., Moysey, R., Gao, F., Sami, M., Boulter, J., Li, Y., Jakobsen, B.K.
Protein Sci.