CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Adenosine deaminase

Enzyme Information

3.5.4.4
Adenosine deaminase.
based on mapping to UniProt P56658
Adenosine + H(2)O = inosine + NH(3).

UniProtKB Entries (1)

P56658
ADA_BOVIN
Bos taurus
Adenosine deaminase

PDB Structure

PDB 2E1W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Design and Synthesis of Non-Nucleoside, Potent, and Orally Bioavailable Adenosine Deaminase Inhibitors
Terasaka, T., Okumura, H., Tsuji, K., Kato, T., Nakanishi, I., Kinoshita, T., Kato, Y., Kuno, M., Seki, N., Naoe, Y., Inoue, T., Tanaka, K., Nakamura, K.
J.Med.Chem.