CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Thymidylate kinase

Enzyme Information

2.7.4.9
dTMP kinase.
based on mapping to UniProt P65248
ATP + dTMP = ADP + dTDP.

UniProtKB Entries (1)

P65248
KTHY_STAAM
Staphylococcus aureus subsp. aureus Mu50
Thymidylate kinase

PDB Structure

PDB 2CCG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of S. Aureus Thymidylate Kinase Reveal an Atypical Active Site Configuration and an Intermediate Conformational State Upon Substrate Binding
Kotaka, M., Dhaliwal, B., Ren, J., Nichols, C.E., Angell, R., Lockyer, M., Hawkins, A.R., Stammers, D.K.
Protein Sci.