CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | GMP reductase |
Enzyme Information
| 1.7.1.7 |
GMP reductase.
based on mapping to UniProt Q9P2T1
Inosine 5'-phosphate + NH(3) + NADP(+) = guanosine 5'-phosphate + NADPH.
-!- Formerly EC 1.6.6.8.
|
UniProtKB Entries (1)
| Q9P2T1 |
GMPR2_HUMAN
Homo sapiens
GMP reductase 2
|
PDB Structure
| PDB | 2C6Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol.
|