CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family GMP reductase

Enzyme Information

1.7.1.7
GMP reductase.
based on mapping to UniProt P36959
Inosine 5'-phosphate + NH(3) + NADP(+) = guanosine 5'-phosphate + NADPH.
-!- Formerly EC 1.6.6.8.

UniProtKB Entries (1)

P36959
GMPR1_HUMAN
Homo sapiens
GMP reductase 1

PDB Structure

PDB 2BWG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Human Guanosine Monophosphate Reductase Gmpr1 in Complex with Gmp
Bunkoczi, G., Haroniti, A., Ng, S., von Delft, F., Gileadi, O., Oppermann, U., Arrowsmith, C., Edwards, A., Sundstrom, M.
To be Published