CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family Alpha-aminoadipic semialdehyde synthase, mitochondrial

Enzyme Information

1.5.1.10
Saccharopine dehydrogenase (NADP(+), L-glutamate-forming).
based on mapping to UniProt P38999
N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NADP(+) + H(2)O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADPH.

UniProtKB Entries (1)

P38999
LYS9_YEAST
Saccharomyces cerevisiae S288C
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]

PDB Structure

PDB 2AXQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution.
Andi, B., Cook, P.F., West, A.H.
Cell Biochem.Biophys.