CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Adenylate kinase mitochondrial

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P27144
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
2.7.4.10
Nucleoside-triphosphate--adenylate kinase.
based on mapping to UniProt P27144
NTP + AMP = NDP + ADP.
-!- Many nucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P27144
KAD4_HUMAN
Homo sapiens
Adenylate kinase 4, mitochondrial

PDB Structure

PDB 2AR7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human adenylate kinase 4, AK4
Filippakopoulos, P., Turnbull, A.P., Fedorov, O., Weigelt, J., Bunkoczi, G., Ugochukwu, E., Debreczeni, J., Niesen, F., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S.
To be Published