CATH Classification

Domain Context

CATH Clusters

Superfamily Mur ligase, C-terminal domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q8DNV6
Q8DNV6_STRR6
Streptococcus pneumoniae R6
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

PDB Structure

PDB 2AM2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
Longenecker, K.L., Stamper, G.F., Hajduk, P.J., Fry, E.H., Jakob, C.G., Harlan, J.E., Edalji, R., Bartley, D.M., Walter, K.A., Solomon, L.R., Holzman, T.F., Gu, Y.G., Lerner, C.G., Beutel, B.A., Stoll, V.S.
Protein Sci.