Homologous Superfamily: 3.90.190.20

Molscript image for 2x5oA03
Representative domain: 2x5oA03
PDB coordinates for domain 2x5oA03

Classification Lineage (3.90.190.20)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.90 Alpha-Beta Complex
3.90.190 Protein-Tyrosine Phosphatase; Chain A
3.90.190.20 Gene3D

Summary of Non-Redundant Representatives
- - - - 8 9 10 17 42

S35 Family Entries in Homologous Superfamily 3.90.190.20 (8)

CATH Level CATH code Representative Domain Representative Keywords Representative Thumbnail Number of Domains
3.90.190.20.1 2x5oA03 D-Glutamine and D-glutamate metabolismUDP-N-acetylmuramoylalanine--D-glutamate ligaseUDP-N-acetylmuramoylalanine-D-glutamate ligase activityUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.Peptidoglycan biosynthesis Molscript image for 2x5oA03 15
3.90.190.20.2 1w78A02 Tetrahydrofolylpolyglutamate synthase activityDihydrofolate synthase.Tetrahydrofolate synthase.Folate biosynthesisProtein binding Molscript image for 1w78A02 2
3.90.190.20.3 1p3dA03 UDP-N-acetylmuramate--L-alanine ligaseD-Glutamine and D-glutamate metabolismUDP-N-acetylmuramate--L-alanine ligase.Haemophilus influenzaeUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] Molscript image for 1p3dA03 10
3.90.190.20.4 1e8cB03 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase.Peptidoglycan biosynthesisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activityProtein binding Molscript image for 1e8cB03 4
3.90.190.20.5 1o5zA02 Thermotoga maritimaFolate biosynthesisFolylpolyglutamate synthase/dihydrofolate synthaseDihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]Metabolic pathways Molscript image for 1o5zA02 1
3.90.190.20.6 1gg4A01 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activityUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D -alanyl-D-alanine ligase [EC:6.3.2.10]UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.Peptidoglycan biosynthesisLysine biosynthesis Molscript image for 1gg4A01 2
3.90.190.20.7 1j6uA03 D-Glutamine and D-glutamate metabolismUDP-N-acetylmuramate--L-alanine ligase.UDP-N-acetylmuramate--L-alanine ligaseThermotoga maritimaUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] Molscript image for 1j6uA03 1
3.90.190.20.8 1jbwA02 Lactobacillus caseiTetrahydrofolate synthase.Folylpolyglutamate synthase Molscript image for 1jbwA02 7

Close Structural Clusters 3.90.190.20 (< 5Å)

Summary of "distant" structural clusters found within this level of CATH.
Cluster ID Example Domain Domains in Cluster Structural Alignment (Core) Structural Alignment (Expanded)
00003.00090.00190.00020/SSG5/1 1e8cB03 4
00003.00090.00190.00020/SSG5/2 1gg4A01 4


Distant Structural Clusters 3.90.190.20 (< 9Å)

Summary of "distant" structural clusters found within this level of CATH.
Cluster ID Example Domain Domains in Cluster Structural Alignment (Core) Structural Alignment (Expanded)
00003.00090.00190.00020/SSGA9/1 1gg4A01 2


The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.90.190.20