CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Rho guanine nucleotide exchange factor (GEF) 7

Enzyme Information

UniProtKB Entries (2)

O55043
ARHG7_RAT
Rattus norvegicus
Rho guanine nucleotide exchange factor 7
Q13191
CBLB_HUMAN
Homo sapiens
E3 ubiquitin-protein ligase CBL-B

PDB Structure

PDB 2AK5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Cbl promotes clustering of endocytic adaptor proteins.
Jozic, D., Cardenes, N., Deribe, Y.L., Moncalian, G., Hoeller, D., Groemping, Y., Dikic, I., Rittinger, K., Bravo, J.
Nat.Struct.Mol.Biol.