CATH Domain 2a98A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.470	D-amino Acid Aminotransferase; Chain A, domain 1
	3.30.470.160	Inositol polyphosphate kinase

Domain Context

CATH Clusters

Superfamily	Inositol polyphosphate kinase
Functional Family	Kinase

Enzyme Information

2.7.1.127

Inositol-trisphosphate 3-kinase.

based on mapping to UniProt Q96DU7

ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.

UniProtKB Entries (1)

IP3KC_HUMAN

Homo sapiens

Inositol-trisphosphate 3-kinase C

PDB Structure

PDB	2A98
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C Hallberg, B.M., Ogg, D., Arrowsmith, C., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Persson, C., Sagemark, J., Schuler, H., Stenmark, P., Thorsell, A.-G., Sundstrom, M., Weigelt, J. To be Published