CATH Classification

Domain Context

CATH Clusters

Superfamily Inositol polyphosphate kinase
Functional Family Kinase

Enzyme Information

2.7.1.127
Inositol-trisphosphate 3-kinase.
based on mapping to UniProt Q96DU7
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.

UniProtKB Entries (1)

Q96DU7
IP3KC_HUMAN
Homo sapiens
Inositol-trisphosphate 3-kinase C

PDB Structure

PDB 2A98
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C
Hallberg, B.M., Ogg, D., Arrowsmith, C., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Persson, C., Sagemark, J., Schuler, H., Stenmark, P., Thorsell, A.-G., Sundstrom, M., Weigelt, J.
To be Published