CATH Classification

Domain Context

CATH Clusters

Superfamily NADP-dependent oxidoreductase domain
Functional Family NAD(P)H-dependent D-xylose reductase xyl1

Enzyme Information

1.1.1.307
D-xylose reductase.
based on mapping to UniProt O74237
Xylitol + NAD(P)(+) = D-xylose + NAD(P)H.
-!- Xylose reductase catalyzes the initial reaction in the xylose utilization pathway, the NAD(P)H dependent reduction of xylose to xylitol.

UniProtKB Entries (1)

O74237
XYL1_CANTE
Yamadazyma tenuis
NAD(P)H-dependent D-xylose reductase

PDB Structure

PDB 1Z9A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis
Kratzer, R., Leitgeb, S., Wilson, D.K., Nidetzky, B.
Biochem.J.