CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family ATP phosphoribosyltransferase

Enzyme Information

2.4.2.17
ATP phosphoribosyltransferase.
based on mapping to UniProt Q02129
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D- ribose 1-diphosphate.
-!- Involved in histidine biosynthesis.

UniProtKB Entries (1)

Q02147
HISZ_LACLA
Lactococcus lactis subsp. lactis Il1403
ATP phosphoribosyltransferase regulatory subunit

PDB Structure

PDB 1Z7M
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Activation of the hetero-octameric ATP phosphoribosyl transferase through subunit interface rearrangement by a tRNA synthetase paralog.
Champagne, K.S., Sissler, M., Larrabee, Y., Doublie, S., Francklyn, C.S.
J.Biol.Chem.