CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.100 | NADP-dependent oxidoreductase domain |
Domain Context
CATH Clusters
| Superfamily | NADP-dependent oxidoreductase domain |
| Functional Family | NAD(P)H-dependent D-xylose reductase xyl1 |
Enzyme Information
| 1.1.1.307 |
D-xylose reductase.
based on mapping to UniProt O74237
Xylitol + NAD(P)(+) = D-xylose + NAD(P)H.
-!- Xylose reductase catalyzes the initial reaction in the xylose utilization pathway, the NAD(P)H dependent reduction of xylose to xylitol.
|
UniProtKB Entries (1)
| O74237 |
XYL1_CANTE
Yamadazyma tenuis
NAD(P)H-dependent D-xylose reductase
|
PDB Structure
| PDB | 1YE4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD(+) and NADP(+).
FEBS Lett.
|