CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Sprouty-related, EVH1 domain containing 2

Enzyme Information

UniProtKB Entries (1)

Q66JG9
SPRE1_XENTR
Xenopus tropicalis
Sprouty-related, EVH1 domain-containing protein 1

PDB Structure

PDB 1XOD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
1.15A Crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family
Harmer, N.J., Sivak, J.M., Amaya, E., Blundell, T.L.
Febs Lett.