CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.470 | D-amino Acid Aminotransferase; Chain A, domain 1 |
|
3.30.470.160 | Inositol polyphosphate kinase |
Domain Context
CATH Clusters
| Superfamily | Inositol polyphosphate kinase |
| Functional Family | Kinase |
Enzyme Information
| 2.7.1.127 |
Inositol-trisphosphate 3-kinase.
based on mapping to UniProt P23677
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.
|
UniProtKB Entries (1)
| P23677 |
IP3KA_HUMAN
Homo sapiens
Inositol-trisphosphate 3-kinase A
|
PDB Structure
| PDB | 1W2D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell
|