CATH Domain 1u2hA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Myosin light chain kinase, smooth muscle

Enzyme Information

2.7.11.1

Non-specific serine/threonine protein kinase.

based on mapping to UniProt Q15772

ATP + a protein = ADP + a phosphoprotein.

-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q15772

SPEG_HUMAN

Homo sapiens

Striated muscle preferentially expressed protein kinase

PDB Structure

PDB	1U2H
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1) Manjasetty, B.A., Niesen, F.H., Scheich, C., Roske, Y., Gotz, F., Behlke, J., Sievert, V., Heinemann, U., Bussow, K. Bmc Struct.Biol.