CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Triosephosphate isomerase

Enzyme Information

5.3.1.1
Triose-phosphate isomerase.
based on mapping to UniProt P04789
D-glyceraldehyde 3-phosphate = glycerone phosphate.

UniProtKB Entries (1)

P04789
TPIS_TRYBB
Trypanosoma brucei brucei
Triosephosphate isomerase, glycosomal

PDB Structure

PDB 1TSI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation.
Verlinde, C.L., Witmans, C.J., Pijning, T., Kalk, K.H., Hol, W.G., Callens, M., Opperdoes, F.R.
Protein Sci.